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How to Read a Certificate of Analysis (COA)

July 17, 20265 min read

A walkthrough of the data fields found on a research peptide COA and what they mean.

A Certificate of Analysis (COA) documents the independent testing results for a specific manufacturing lot, including purity percentage, testing date, analytical method, and supporting chromatography or mass spectrometry data. This article walks through each field on a typical COA — lot number, purity, molecular weight confirmation, and appearance — and explains why researchers should always cross-reference the lot number printed on a vial against the COA on file before beginning a study.

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This article is provided for general laboratory education only. It does not constitute usage instructions, dosing guidance, or medical advice, and describes no human or animal application.